. 2013 Mar 21;56(8):3217–3227. doi: 10.1021/jm301588r

Table 1. IC₅₀ Values of Compounds 3 and 12–16 against BRD4(1) and CREBBP.

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Protein and peptide concentration: 50 nM.

Protein and peptide concentration: 200 nM. Heat map shows relative IC₅₀ values obtained in an ALPHA assay.³⁰ Red indicates low IC₅₀ values, and green indicates high IC₅₀ values. Ranges in parentheses represent 95% confidence intervals resulting from sigmoidal curve fitting to duplicate data.

Values taken from ref (24).

Table 1. IC50 Values of Compounds 3 and 12–16 against BRD4(1) and CREBBP.

Table 1. IC₅₀ Values of Compounds 3 and 12–16 against BRD4(1) and CREBBP.