. 2013 Mar 21;56(8):3217–3227. doi: 10.1021/jm301588r

Table 2. IC₅₀ Values of Compounds 8, 9, 17, 21–23 against BRD4(1).

graphic file with name jm-2012-01588r_0012.jpg

graphic file with name jm-2012-01588r_0013.jpg

Protein and peptide concentration: 50 nM.

Protein and peptide concentration: 50 nM. Heat map shows relative IC₅₀ values obtained in an ALPHA assay.³⁰ Red indicates low IC₅₀ values, and green/yellow indicates high IC₅₀ values. Ranges in parentheses represent 95% confidence intervals resulting from sigmoidal curve fitting to duplicate data.

Table 2. IC50 Values of Compounds 8, 9, 17, 21–23 against BRD4(1).

Table 2. IC₅₀ Values of Compounds 8, 9, 17, 21–23 against BRD4(1).