Table 2.

Cytokine expression (ratio and fold change) for THP-1 cocultures with MCF-7 and SUM149 cells^a

	Cytokine	Ratio comparing THP- 1:MCF-7 cocultures to monocultures	Fold-change due to THP-1:MCF-7 coculture	Ratio comparing THP-1:SUM149 cocultures to monocultures	Fold-change due to THP-1:SUM149 coculture
More substantially altered in SUM149 cocultures	NAP-2	0.74	−1.35	8.95*	7.95*
	MCP-1	0.54*	−1.85*	5.06*	4.06*
	Osteoprotegerin	1.39	0.39	2.56*	1.56*
	IL-1 b	0.71	−1.41	1.83*	0.83*
	MCP-3	0.62	−1.61	1.83*	0.83*
	MIG	0.80	−1.25	1.68*	0.68*
	IL-5	0.75	−1.33	1.51*	0.51*
	GRO	0.63*	−1.59*	0.09*	−11.11*
	RANTES	0.42*	−2.38*	0.41*	−2.44*
	Fractalkine	0.51*	−1.96*	0.42*	−2.38*
	IL-12 p40p70	0.74	−1.35	0.42*	−2.38*
	HGF	0.59*	−1.69*	0.46*	−2.17*
	MIP-1b	0.61*	−1.64*	0.52*	−1.92*
	PIGF	0.69	−1.45	0.55*	−1.82*
	TGF-b3	0.67	−1.49	0.55*	−1.82*
	GDNF	0.64*	−1.56*	0.58*	−1.72*
	MIF	0.73	−1.37	0.62*	−1.61*
	GRO-a	0.72	−1.39	0.63*	−1.59*
	IL-4	0.68	−1.47	0.63*	−1.59*
	IGFBP-1	0.72	−1.39	0.63*	−1.59*
	FGF-7	0.78	−1.28	0.64*	−1.56*
	FGF-4	0.70	−1.43	0.64*	−1.56*
	PARC	0.69	−1.45	0.65*	−1.54*
More substantially altered in MCF-7 cocultures	LIF	2.13*	1.13*	1.88*	0.88*
	Osteopontin	1.90*	0.90*	1.70*	0.70*
	IGFBP-2	0.38*	−2.63*	0.39*	−2.57*
	ENA-78	0.46*	−2.17*	0.49*	−2.04*
	MDC	0.47*	−2.13*	0.55*	−1.82*
	IL-13	0.55*	−1.82*	0.69	−1.44
	Eotaxin-2	0.59*	−1.69*	0.60*	−1.66*
	IL-1a	0.61*	−1.64*	1.23	0.23
	IL-2	0.62*	−1.61*	1.09	0.09
	GCSF	0.63*	−1.59*	0.96	−1.04
	IL-15	0.65*	−1.54*	1.03	0.03

^aStatistically significant upregulation or downregulation is denoted with an asterisk.

Bold indicates upregulation.