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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Inorg Chem. 2013 Mar 21;52(7):4084–4096. doi: 10.1021/ic400227k

Table 3.

Time required to reach 80% of R1 (t = 0) and values of R1 (t = 24 h) for Gd complexes

Compound Time to 80%
R1
[h]
% R1
(t = 24 h)
% R1
(t = 24 h)
phosphate
only
[Gd(DO2A)] N/Aa 0 0
[Gd(DTPA)] 2.96 45 inert
[Gd(DO3A)] inert inert inert
[Gd(HP-DO3A)] inert inert inert
[Gd(L1)] < 0.5 0 18
[Gd(L2)] 11.4 64 96
[Gd(L3)] 1.81 11 58
[Gd(L4)] < 0.5 0 0
[Gd(L5)] 1.04 0 25
[Gd(L6)] 1.30 9 16

Values calculated from biexponential fits of the experimental data.

a

Value could not be reliably determined due to nonstandard behavior.