Table 5.

Heterogeneity test results and sample size information for the meta-analyses reported in Table 4

	Unadjusted		Adjusted for Age Only		Adjusted for Age and Additional Covariates
	N	p-value from Q-test	N	p-value from Q-test	N	p-value from Q-test
All available data	693	0.000	284	0.409	404	0.999
Non-estimated death rate only	554	0.000	164	0.995	335	0.999
Non-estimated SE only	171	0.000	200	0.814	342	0.999
By subjective quality score
Low	99	0.643	48	0.000	2	0.920
Average	448	0.000	115	0.999	104	0.999
High	146	0.076	121	0.988	298	0.999
Gender
Women	307	0.015	138	0.021	179	0.999
Men	360	0.000	139	0.999	168	0.999
Mean age
20 – 29.9	20	0.000	0	--	0	--
30 – 39.9	25	0.344	0	--	3	0.869
40 – 49.9	82	0.000	4	0.206	33	0.018
50 – 59.9	110	0.920	8	0.317	27	0.999
60 – 69.9	135	0.119	52	0.998	107	0.999
70 – 79.9	117	0.670	35	0.999	52	0.999
≥ 80	204	0.042	185	0.007	182	0.999
Region
Scandinavia	60	0.909	105	0.000	92	0.999
United States	213	0.832	50	0.999	150	0.999
United Kingdom	111	0.403	60	0.999	24	0.999
East Europe	27	0.002	8	0.823	2	0.633
West Continental Europe	240	0.000	54	0.200	101	0.999
China and Japan	6	0.007	6	0.732	24	0.946
Bangladesh and Lebanon	36	0.839	1	--	11	0.940
Enrollment start year
1766 – 1939	2	0.119	21	0.999	68	0.999
1940 – 1949	100	0.682	3	0.988	0	--
1950 – 1959	102	0.997	9	0.707	0	--
1960 – 1969	251	0.000	77	0.000	37	0.990
1970 – 1979	98	0.000	85	0.999	83	0.999
1980 – 1989	121	0.005	61	0.999	148	0.999
1990 – 1999	17	0.382	24	0.000	68	0.431
Follow-up duration
6 months or less	53	0.999	40	0.947	33	0.999
1 year	125	0.000	24	0.396	30	0.999
2 years	77	0.088	20	0.000	15	0.000
3 years	89	0.049	13	0.000	7	0.907
4 years	16	0.872	16	0.000	7	0.934
5 years	18	0.631	5	0.027	13	0.999
6 years	11	0.984	25	0.695	32	0.987
7 years	8	0.211	16	0.962	24	0.999
8 years	23	0.727	3	0.003	10	0.995
9 years	5	0.023	6	0.111	26	0.999
10 years	0	--	36	0.998	36	0.999
11 years	7	0.922	21	0.999	14	0.962
12 years	0	--	2	0.553	12	0.304
13 years	25	0.999	5	0.993	6	0.998
14 years	9	0.702	4	0.703	4	0.950
15 years	0	--	2	0.794	27	0.819
16–20 years	15	0.000	19	0.988	11	0.993
21–25 years	1	--	5	0.991	14	0.977
More than 25 years	17	0.011	7	0.903	54	0.999