Table 1.
Characteristic | Diagnostic Groups
|
P* | Post hoc | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Dementia With Psychosis (n=56)
|
Mood Disorder With Psychosis (n=49)
|
Schizophrenia (n=65)
|
PTSD (n=33)
|
|||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||
Age, yr | 77.2 | 9.8 | 67.1 | 13.2 | 58.3 | 10.6 | 59.7 | 10.5 | <0.001 | D> M> S, P |
Education level, yr | 13.7 | 2.8 | 14.0 | 3.1 | 12.4 | 2.8 | 13.7 | 2.5 | <0.05 | D, P, M >S |
Duration of antipsychotic treatment, mo | 44.4 | 36.1 | 129.4 | 133.1 | 253.3 | 162.9 | 173.4 | 160.6 | <0.001 | S>P, M>D |
Number of metabolic syndrome conditions | 2.8 | 1.3 | 3.0 | 1.4 | 2.9 | 1.5 | 3.3 | 1.4 | 0.459 | — |
BMI | 26.1 | 5.0 | 29.5 | 7.8 | 29.8 | 6.8 | 30.4 | 4.3 | <0.001 | D<M, S, P |
Diastolic blood pressure, mm Hg | 69.4 | 9.7 | 69.3 | 8.6 | 72.8 | 9.1 | 75.1 | 9.7 | 0.015 | D, M <P |
Systolic blood pressure, mm Hg | 126.2 | 18.6 | 126.4 | 15.8 | 123.4 | 19.7 | 132.7 | 15.2 | 0.089 | — |
Waist circumference, in | 36.9 | 5.2 | 40.3 | 7.2 | 41.0 | 6.4 | 39.9 | 7.0 | 0.002 | D<M, S, P |
Fasting glucose level, mg/dL | 100.0 | 23.1 | 109.9 | 44.6 | 119.7 | 78.5 | 114.2 | 41.3 | 0.088 | — |
HDL cholesterol level, mg/dL | 51.9 | 18.7 | 44.8 | 12.6 | 44.3 | 18.5 | 41.4 | 10.3 | 0.012 | D>M, S, P |
Triglyceride level, mg/dL | 123.5 | 115.1 | 140.5 | 87.6 | 149.6 | 120.6 | 127.3 | 61.1 | 0.558 | — |
Categorical variables | n | % | n | % | n | % | n | % | ||
| ||||||||||
Sex | ||||||||||
Male | 31 | 55 | 30 | 61 | 48 | 74 | 29 | 88 | <0.01 | D<S, P; M<P |
Female | 25 | 45 | 19 | 39 | 17 | 26 | 4 | 12 | (% male) | |
Ethnicity | ||||||||||
White | 47 | 84 | 40 | 82 | 42 | 64 | 21 | 64 | <0.05 | D, M > S, P |
Nonwhite | 9 | 16 | 9 | 18 | 23 | 37 | 12 | 36 | (% White) | |
On antidiabetic drugs | 6 | 11 | 11 | 22 | 16 | 25 | 7 | 21 | 0.351 | — |
On statins | 20 | 34 | 22 | 45 | 15 | 23 | 15 | 45 | 0.058 | — |
On antihypertensive drugs | 30 | 54 | 29 | 59 | 28 | 43 | 22 | 67 | 0.234 | — |
Currently on antipsychotics† | 42 | 75 | 46 | 94 | 55 | 89 | 30 | 91 | <0.01 | M, P>D |
Welch ANOVA for continues variables and χ2 for categorical variables.
The percentage of patients taking atypical antipsychotics or rate of olanzapine use was not significantly different between the diagnostic groups.
D indicates dementia with psychosis; M, mood disorder with psychosis; P, PTSD; S, schizophrenia.