Table 1.

Relative toxicities of OA and derivatives to mice by intraperitoneal injection and relative inhibitory activities toward protein phosphatases.

Compound	Relative toxicity to mice (i.p. injection)	Relative inhibition of PP2A	Relative inhibition of PP1
OA	1.0	1.0	1.0
DTX-1	1.0 [11]	1.6–2.4 [45,48,49]	0.4–0.9 [45,48]
DTX-2	0.6 [7]	0.5 [7]	-
DTX-4	0.3 [13]	0.002 [51]	-
7-O-palmitoyl-OA	0.05 [14]	<0.0003 [45]	<0.00005 [45]
7-O-docosahexaenoyl-OA	0.5 [14]	<0.0003 [45,50]	-