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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Arch Pathol Lab Med. 2012 May;136(5):517–526. doi: 10.5858/arpa.2011-0147-OA

Fig 2. Normal structures of bladder wall and flat intraurothelial lesions without atypia.

Fig 2

Multiphoton microscopy (MPM) image (A) and corresponding H&E image (B) at low magnification showing clear demarcation between normal urothelium (a) and lamina propria (b). Lamina propria is composed of collagen bundles (red) and elastin fibers (green). MPM image (C) and corresponding H&E image (D) at high magnification showing multi-layered urothelium and superficial umbrella cells. Umbrella cells in each image are boxed and shown at higher digital zoom in the inset. MPM image (E) and corresponding H&E image (F) at low magnification showing von Brunn nests, some with cystic dilatation (cystitis cystica; arrow). (MPM magnifications: A=120X, C=240X, E=306X;H&E magnifications: B=40X, D=200X, F=200X).