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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Arch Pathol Lab Med. 2012 May;136(5):517–526. doi: 10.5858/arpa.2011-0147-OA

Fig 5. Papillary urothelial carcinoma, high grade, non-invasive.

Fig 5

Multiphoton microscopy (MPM) image (A) and corresponding H&E image (B) at low magnification showing the papillary nature of the lesion (complex, thickened papillae with thin fibrovascular cores; arrow). MPM image (C) and corresponding H&E image (D) at high magnification showing thickened fibrovascular cores and disorderly arrangement of cells. MPM image (E) and corresponding H&E image (F) at high magnification showing cells with marked pleomorphism, high Nuclear:Cytoplasmic (N:C) ratio, and hyalinized fibrovascular cores. MPM magnifications: A = 48X, C = 240X, E = 480X; H&E magnifications: B=40X, D=200X, F=400X).