Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 May 1.

Published in final edited form as: DNA Repair (Amst). 2009 Jul 18;8(10):1179–1189. doi: 10.1016/j.dnarep.2009.06.006

Fig. 6 — TREX1 clears apoptotic DNA in drug-treated dying cells. Analyzed by flow cytometry, the DNA content of CPT-treated RKO/TREX1 cells for 24 h with or without doxycycline was studied. (A, a–d) The cells in 1.5×10⁴ events were gated and divided into two populations: the live (FSC-H: 550–1,000) and the apoptotic cells (FSC-H: 200–530). (B, a–d). The DNA content of the live cell population was distributed into subG1 and G1-S-G2-M areas. (C, a–d). The DNA content in the apoptotic cell population under log format was distinctly distributed into two sub-areas. Data represent typical experiments that were repeated three times with similar results.

Fig. 6 — TREX1 clears apoptotic DNA in drug-treated dying cells. Analyzed by flow cytometry, the DNA content of CPT-treated RKO/TREX1 cells for 24 h with or without doxycycline was studied. (A, a–d) The cells in 1.5×10⁴ events were gated and divided into two populations: the live (FSC-H: 550–1,000) and the apoptotic cells (FSC-H: 200–530). (B, a–d). The DNA content of the live cell population was distributed into subG1 and G1-S-G2-M areas. (C, a–d). The DNA content in the apoptotic cell population under log format was distinctly distributed into two sub-areas. Data represent typical experiments that were repeated three times with similar results.