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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Cancer. 2010 Nov 29;117(9):1917–1927. doi: 10.1002/cncr.25691

Table 4.

Risk Model Performance in the Derivation and Validation Datasets

Derivation and Validation Models Severe or Febrile Neutropenia Risk Based on Median Predicted Risk
Derivation Validation

  • Model Performance

    • Sensitivity: 90.0% [87.8, 92.4]

    • Specificity: 58.9% [56.6, 61.1]

  • Model Predictive Value

    • Positive: 34.2% [31.5, 36.9]

    • Negative: 96.1% [94.8, 97.1]

  • Model Likelihood Ratio

    • Positive: 2.19 [2.05, 2.33]

    • Negative: 0.17 [0.13, 0.23]

  • Model Diagnostic Odds Ratio:

    • 12.81 [9.29, 17.67]

  • Model Performance

    • Sensitivity: 85.0% [80.1, 88.9]

    • Specificity: 58.7% [55.5, 61.8]

  • Model Predictive Value

    • Positive: 36.1% [32.3, 40.0]

    • Negative: 93.4% [91.1, 95.2]

  • Model Likelihood Ratio

    • Positive: 2.06 [1.87, 2.26]

    • Negative: 0.26 [0.19, 0.35]

  • Model Diagnostic Odds Ratio:

    • 8.03 [5.56, 11.62]