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Sample plots of fractional tissue oxygen extraction (FTOE) across sleep-wake states from an infant with seizures of uncertain etiology (panel A) and cerebral rSO2 values from an infant with hypoxic ischemic encephalopathy (panel B). Boxplots demonstrate the median, 25th, 75th, 10th, and 90th percentiles, with outliers. For each subject, there were statistically significant differences among sleep-wake states (p<0.0001).
