Table 2.
Pooled near-infrared spectroscopy data across sleep-wake states for ten critically-ill neonates.
| Awake | Quiet Sleep |
Active Sleep |
Kruskal -Wallisa |
Pair-Wise Comparisons (Mann-Whitney p-valuea) |
|||
|---|---|---|---|---|---|---|---|
| Median(IQ R) |
Median(IQ R) |
Median(IQ R) |
p-value | Awake- Quiet |
Quiet- Active |
Awake- Active |
|
| Left rSO2 | 76.6 (5.8) | 78.2 (13.7) | 77.4 (8.0) | <0.0001 | <.0001 | 0.0014 | <.0001 |
| Right rSO2 | 80.0 (7.8) | 79.0 (11.4) | 77.5 (8.2) | <0.0001 | 0.7515 | <.0001 | <.0001 |
| Systemic rSO2 | 72.5 (17.6) | 84.8 (11.8) | 78.8 (14.0) | <0.0001 | <.0001 | <.0001 | <.0001 |
| SaO2 | 96.0 (5.6) | 97.4 (3.4) | 96.8 (3.5) | <0.0001 | <.0001 | <.0001 | <.0001 |
| Left FTOE | 0.19 (0.09) | 0.18 (0.15) | 0.19 (0.11) | <0.0001 | 0.0353 | <.0001 | 0.4640 |
| Right FTOE | 0.17 (0.09) | 0.19 (0.13) | 0.20 (0.10) | <0.0001 | 0.0066 | <.0001 | <.0001 |
| Systemic FTOE | 0.24 (0.18) | 0.13 (0.12) | 0.19 (0.15) | <0.0001 | <.0001 | <.0001 | <.0001 |
| Heart Rateb | 137.0 (27.0) | 114.2 (25.8) | 117.3 (23.0) | <0.0001 | <.0001 | <.0001 | <.0001 |
| Mean BPb | 56.0 (20.0) | 49.0 (15.0) | 49.0 (20.0) | <0.0001 | <.0001 | 0.10 | <.0001 |
IQR = Interquartile range
SaO2=systemic oxygen saturation
FTOE = Fractional Tissue Oxygen Saturation
Mean BP = Mean arterial blood pressure
a
Applying a Bonferroni correction, with 9 comparisons across 3 behavioral states, a p-value less than 0.002 is considered significant.
b
Data for Heart Rate and Mean Blood Pressure were available for 8 of the 10 subjects.