. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Arch Biochem Biophys. 2012 Oct 27;535(1):3–13. doi: 10.1016/j.abb.2012.10.011

Table 1.

Maximal tension (mN mm^-2) and rate of ATPase activity (pmol mm^-3 s^-1) estimated in fibers from normal or PTU-treated mice at SL 2.0 or 2.2 μm. Hill s equation was fitted to pCa-tension relationships to estimate myofilament Ca²⁺ sensitivity (pCa₅₀) and cooperativity (n_H) parameter estimates. Values are mean ± SEM. Number of determinants is at least 10 for each group.

	Fibers from Normal Mice (α -MHC)		Fibers from PTU-Treated Mice (β -MHC)
SL	2.0 μm	2.2 μm	2.0 μm	2.2 μm
Max Tension	38.01±0.62	43.75±1.53^*	46.75±0.90 ^α	52.84±2.37^*^α
Max ATPase	319.72±8.99	319.83±18.60	163.67±5.15 ^α	145.90±5.19 ^α
pCa₅₀	5.73±0.01	5.78±0.01^*	5.81±0.01 ^α	5.85±0.01^* ^α
n_H	3.08±0.22	2.16±0.09^*	2.81±0.07 ^α	2.46±0.06^* ^α

- p < 0.05 vs. short SL in same (α-MHC or β-MHC) group of fibers;

^α

- p < 0.05 vs. α-MHC fibers at same SL.