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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Cyst Fibros. 2013 Jan 26;12(5):445–453. doi: 10.1016/j.jcf.2012.12.011

Table 4.

Protein and Arginine kinetics in the CF group after intake of the EAA and TAA mixture

TAA EAA
Protein synthesis 185.4 ± 8.7 197.1 ± 11.6**
Protein breakdown 159.6 ± 7.0 171.1 ± 10.7
Net Protein synthesis 25.8 ± 3.0 38.2 ± 4.6***
Splanchnic extraction 0.50 ± 0.04 0.47 ± 0.05p=0.06
WbRa Leucine 372.8 ± 17.7 645.5 ± 41.6***
WbRa Arginine 439.7 ± 33.3 394.5 ± 31.4***
WbRa Citrulline 47.8 ± 3.8 44.8 ± 3.0
Q Citrulline to Arginine 52.2 ± 5.0 47.1 ± 4.1p=0.09
Q Arginine to Citrulline 1.3 ± 0.3 0.9 ± 0.2

Values are means ± SEM and expressed in nmol/kg ffm/3h. CF: Cystic Fibrosis, WbRa: Whole body rate of appearance, Q Citrulline to Arginine: de novo arginine synthesis rate, Q Arginine to Citrulline: Nitric oxide production rate. Significance of difference after intake of the total amino acid mixture (TAA) and the essential amino acid mixture (EAA):

**

: P < 0.01,

***

: P<0.001.