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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Clin J Pain. 2013 Jul;29(7):613–620. doi: 10.1097/AJP.0b013e31826dfb13

Table 3.

Relationship (p value) between cerebral and physiological measures, and clinical factors (univariate analysis) during chest-drain removal.

Parameter Δ[HbO2] Δ[HbH] ΔMAP ΔHR ΔSaO2
T1–T0
   ΔMAP
   ΔHR 0.19 (.035)1
   ΔSaO2
   Morphine −137.78 (.005)1
   Midazolam −114.87 (.017)1 −71.27 (.012)
   Age
   Weight 4.6 (.032)
T2–T0
   ΔMAP
   ΔHR
   ΔSaO2
   Morphine
   Midazolam
   Age −1.94 (.044)1
   Weight 3.93 (.029) −1.46 (.002)
T2–T1
   ΔMAP
   ΔHR
   ΔSaO2
   Morphine −82.54 (.002)1 −90.24 (.022)
   Midazolam 105.97 (.029)1 −63.7 (.015)1
−137.49 (.008)2
−146.63 (.005)
   Age 2.9 (.044)
   Weight −1.11 (.017)
1

Left hemisphere;

2

Right hemisphere;

[HbO2]: oxygenated hemoglobin concentration; [HbH]: deoxygenated hemoglobin concentration; MAP: mean arterial blood pressure; HR: heart rate; SaO2 arterial blood oxygen saturation.

T0 baseline; T1 tactile stimulus; T2 noxious stimulation (chest-drain removal).