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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Atherosclerosis. 2013 Feb 18;228(1):181–187. doi: 10.1016/j.atherosclerosis.2013.02.004

Table 4.

Associations of DHA with plasma lipids and lipoproteins across APOE genotypes12

E2 (n=333) E3 (n=1459) E4(n=548) p-value interaction
Slope (p-value) Slope (p-value) Slope (p-value)
Lipoprotein characteristics
Small LDL conc. (nmol/L) -2.99 (0.90) -3.37 (0.88) 27.34 (0.25) 0.01
Medium HDL conc. (μmol/L) -1.46 (<0.001) -1.09 (0.004) -1.48(<0.001) 0.05
1

Values are the slope of EPA on each plasma lipid or lipoprotein in each APOE genotype group (p-values in parentheses). The p-value for interaction is calculated based on test for equality for the three APOE genotype groups.

2

Adjusted for age, sex, race, field center, ancestry informative marker principal components (PC1-PC5), education, smoking status, alcohol use, total intentional exercise, BMI, diabetes. Triglycerides was included as a covariate for outcomes other than triglycerides