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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: FEBS J. 2013 Feb 11;280(10):2194–2206. doi: 10.1111/febs.12134

Figure 2. SSTN blocks early onset of microvessel outgrowth in fibrin gels.

Figure 2

A. Segments of mouse aorta explanted to fibrin gels in the presence of 20 ng/mL FGF are treated from Day 0 to Day 10 with a range of SSTN92-119 concentrations or 10 μg/mL αV-integrin blocking antibody (mAb M9), followed by quantification of microvessel outgrowth. B. Explants cultured in 20 ng/mL FGF are treated with SSTN92-119 (3 μM) at the times shown and total length of microvessel outgrowth shown as a percentage of FGF alone. Error bars (S.E.M) represent data from a minimum of triplicate explants from two experiments.

(Rapraeger et al.)