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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Trends Endocrinol Metab. 2011 Oct 27;23(1):23–31. doi: 10.1016/j.tem.2011.09.003

Figure 1.

Figure 1

Galectins promote a diverse range of responses when they contact leukocytes. Galectin-effects on innate and adaptive immune cells are depicted around the 3D model of galectin-1 dimer (1GZW) [31,55]. These effects are context-dependent and relate to the type of galectins and their intra- or extracellular localization, as well as to the type of cells and their activation and/or differentiation status [10,12,14]. Galectins as well as most types of immune cells (e.g. T cells, neutrophils, macrophages) depicted in the figure are abundant at the maternal-fetal interface. Figure adapted from [31], © Taylor & Francis.