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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Placenta. 2013 Mar 1;34(4):360–368. doi: 10.1016/j.placenta.2013.01.012

Figure 1. Histologic and immunophenotypic characteristics of ‘trophoblast islands of the chorionic connective tissue’ (TICCT).

Figure 1

a, c: Scattered cells with amphophilic cytoplasm in the chorionic connective tissue layer (arrows) in normal term delivery cases at the gestational ages of 41.9 and 40.0 weeks, respectively. b, d: Double immunofluorescence staining showing cytokeratin-7 (green; Alexa Fluor® 488) and HLA-G (red; Alex Fluor® 594) positive extravillous trophoblasts in the chorionic connective tissue layer (*). The border between the chorionic trophoblast layer and the connective layer is indicated by arrowheads.