Table 2.
Clinical characteristics of preterm delivery cases and a TICCT positive rate
| TICCT (−) | TICCT (+) | p value | adjusted p valuea | |
|---|---|---|---|---|
| Cases: number [n (%)] | 758 (79.3%) | 198 (20.7%) | ||
| Ethnicity [n (%)] | <0.001 | <0.001 | ||
| African-American | 302 (39.8%) | 129 (65.2%) | ||
| Hispanic | 456 (60.2%) | 69 (34.8%) | ||
| Maternal age (years, mean ± s.d.) | 26.0 (± 7.1) | 25.4 (± 6.6) | 0.259 | |
| Parity [n (%)] | 0.356 | |||
| Nulliparity | 299 (39.4%) | 71 (35.9%) | ||
| Multiparity | 459 (60.6%) | 127 (64.1%) | ||
| GAD (weeks, mean ± s.d.) | 33.0 (± 3.1) | 34.5 (± 2.1) | <0.001 | 0.001 |
| Fetal sex [n (%)] | <0.001 | <0.001 | ||
| Male | 453 (59.8%) | 81 (40.9%) | ||
| Female | 305 (40.2%) | 117 (59.1%) | ||
| Birth weight (grams, mean ± s.d.) | 2026 (± 677) | 2271 (± 619) | <0.001 | <0.001b |
| Diagnosis [n (%)] | 0.879 | |||
| Preterm labor | 324 (42.7%) | 89 (44.9%) | ||
| pPROM | 240 (31.7%) | 52 (26.3%) | ||
| Preeclampsia | 194 (25.6%) | 57 (28.8%) | ||
| Spontaneous labor [n (%)] | 0.058 | |||
| No | 344 (45.4%) | 75 (37.9%) | ||
| Yes | 414 (54.6%) | 123 (62.1%) | ||
| ACA [n (%)] | 0.911 | |||
| No | 633 (83.5%) | 166 (83.8%) | ||
| Yes | 125 (16.5%) | 32 (16.2%) | ||
| MVU [n (%)] | 0.857 | |||
| No | 613(80.9%) | 159 (80.3%) | ||
| Yes | 145(19.1%) | 39 (19.7%) | ||
| FVTOD [n (%)] | 0.109 | |||
| No | 710 (93.7%) | 179 (90.4%) | ||
| Yes | 48 (6.3%) | 19 (9.6%) | ||
| CPI [n (%)] | <0.001 | 0.003 | ||
| No | 456 (60.2%) | 147 (74.2%) | ||
| Yes | 302 (39.8%) | 51 (25.8%) |
GAD: Gestational age at delivery, pPROM: preterm prelabor rupture of membranes, ACA: acute chorioamnionitis, MVU: maternal vascular underperfusion, FVTOD: fetal vascular thrombo-occlusive disease, CPI: chronic placental inflammation.
a
Adjustment for ethnicity, gestational age at delivery, fetal sex, and chronic inflammation of the placenta was based on a multiple logistic regression model.
b
Without adjustment for gestational age at delivery.