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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: ChemMedChem. 2013 Jan 29;8(3):385–395. doi: 10.1002/cmdc.201200585

Table 14.

Acidity of a series of mercaptoazoles.[77]

graphic file with name nihms-455683-t0051.jpg
Compd n X Y Z pKa
80 0 CH CH N 11.6
81 1 CH CH N 9.8
82 2 CH CH N 8.67
83 0 N CH N 9.5
84 1 N CH N 7.38
85 2 N CH N 6.23
86 0 N N CH 8.2
87 1 N N CH 6.09
88 2 N N CH 5.15
89 0 CO NH N 7.85
90 1 CO NH N 5.2
91 2 CO NH N 4.79