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Stimulation of cAMP accumulation in CHO cells expressing human β3, β2, and β1 adrenergic receptors by acylsulfonamides and sulfonylureas.[27]
| ||||
|---|---|---|---|---|
| Compd | R | pEC50 | ||
| β 3 | β 2 | β 1 | ||
| 26 |
|
7.8 | 7.3 | 7.1 |
| 27 |
|
8.3 | 7.7 | 7.0 |
| 28 |
|
9.1 | 7.5 | 6.1 |
| 29 |
|
7.8 | 6.6 | 6.4 |
