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. Author manuscript; available in PMC: 2013 Jul 10.
Published in final edited form as: Mol Cell. 2012 Nov 15;49(1):158–171. doi: 10.1016/j.molcel.2012.10.013

Figure 1. GR, AP-1 and NF-κB cistromes intersect.

Figure 1

a) Area-proportional Venn diagram of GR cistromes in unstimulated (orange) and stimulated (red) macrophages. b) Motif analysis of the GR cistrome in macrophages treated with Dex only. c) Area-proportional Venn diagram showing the overlap between GR, c-Jun and p65 ChIP-Seq peaks in macrophages treated with LPS and Dex. Genomic regions with significant peak scores were merged and given a 100bp margin for co-occurrence. d) Globally enriched motifs within the GR, c-Jun and p65 cistromes in response to LPS. Tables show the top five to six statistically overrepresented binding sites.