Table 3.
Gene | SNP | Model | Never-smokers
|
Ever-smokers
|
||
---|---|---|---|---|---|---|
HR (95% CI)a | P | HR (95% CI)a | P | |||
SYK | rs290229 | DOM | 1.58 (1.23–2.03) | 3.03 × 10−4 | 1.12 (0.94–1.33) | 0.214 |
CD74 | rs1056400 | DOM | 0.58 (0.43–0.78) | 3.54 × 10−4 | 0.93 (0.75–1.15) | 0.487 |
BMP8A | rs698141 | DOM | 1.89 (1.33–2.68) | 4.04 × 10−4 | 1.06 (0.81–1.40) | 0.655 |
IL17RA | rs879576 | DOM | 0.57 (0.41–0.78) | 5.49 × 10−4 | 0.89 (0.72–1.10) | 0.266 |
CD38 | rs10805347 | REC | 0.45 (0.28–0.72) | 7.93 × 10−4 | 0.91 (0.67–1.24) | 0.557 |
Abbreviations: DOM, dominant model; REC, recessive model.
Adjusted according to age, sex, clinical stage, and treatment regimen. Boldface: P < 0.1.