Figure 3.
Kidney function and serum creatinine. Mean (± SD) serum creatinine (top panel), calculated individual glomerular filtration rates (GFR; middle panel), and individual inulin plasma/urine ratios (bottom panel) before and 10 h after determination of brain death. The group means for GFR and inulin ratios are demarcated with bars. Serum creatinine and the plasma/urine inulin ratios significantly increased and GFR significantly decreased in the untreated control cohort after brain death (p < 0.05; brackets with asterisks). In the 20 ppm ethyl nitrite (ENO) treatment group, the before and after brain death values for all three parameters were not statistically different.