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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Immunol. 2010 Sep 29;185(9):5444–5452. doi: 10.4049/jimmunol.0903802

FIGURE 3.

FIGURE 3

SRC-3−/− mice exhibit more severe bacterial outgrowth and dissemination during E. coli-induced peritonitis. Bacterial loads in peritoneal fluid (A), blood (B), liver (C), spleen (D) and lung (E) at 6 and 20 h after infection with E. coli. Data are the means + SD of five mice per time point. **p<0.01. F, SRC-3 deficiency had no effect on antibacterial activity of serum. G and H, Expression of antimicrobial protein lipocalin-2 (Lcn2) in the liver (G) or spleen (H) from both types of mice with or without infection of E. coli was analyzed by real-time PCR. Data are the means + SD of four mice per group.