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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Immunol. 2010 Sep 29;185(9):5444–5452. doi: 10.4049/jimmunol.0903802

FIGURE 6.

FIGURE 6

SRC-3 regulates the expression of catalase in macrophages. A, Catalase promoter activity was increased in RAW264.7 cells co-transfected with SRC-3 expression. Data are presented as the means + SD (n=3). ** p<0.01. (B) Catalase promoter activity was decreased in RAW264.7 cells co-transfected with SRC-3 specific siRNA. Inserted: western blot analysis revealed a down-regulated of SRC-3 protein by SRC-3 siRNA but not control siRNA. Data are presented as the means + SD (n=3). * p<0.05. C, SRC-3 was associated with the promoter of catalase. Upper panel: positions of the subfragments detected in ChIP assay; Lower panel: ChIP assay showed that SRC-3 was associated with the promoter of catalase. IgG: goat IgG, α-SRC-3: anti-SRC-3 goat IgG.