Table 1. Gene ontology enrichment on the list of amputation-specific genes selected by two-way ANOVA analysis.
| # Array | # List | P-value | GO term |
| 1059 | 21 | 3.11E-09 | tissue development |
| 493 | 16 | 3.18E-10 | epithelium development |
| 389 | 10 | 7.02E-06 | tissue morphogenesis |
| 308 | 10 | 8.75E-07 | morphogenesis of an epithelium |
| 184 | 7 | 1.53E-05 | morphogenesis of a branching structure |
| 161 | 7 | 6.38E-06 | morphogenesis of a branching epithelium |
| 12 | 3 | 1.68E-05 | branch elongation of an epithelium |
| 2188 | 26 | 1.02E-06 | organ development |
| 260 | 10 | 1.85E-07 | gland development |
| 113 | 8 | 3.16E-08 | gland morphogenesis |
| 265 | 8 | 1.97E-05 | epidermis development |
| 704 | 13 | 1.01E-05 | organ morphogenesis |
| 185 | 8 | 1.40E-06 | urogenital system development |
| 223 | 8 | 5.61E-06 | reproductive structure development |
| 46 | 6 | 4.53E-08 | prostate gland development |
| 31 | 6 | 3.75E-09 | prostate gland morphogenesis |
| 30 | 6 | 3.04E-09 | prostate gland epithelium morphogenesis |
| 15 | 4 | 4.34E-07 | branching involved in prostate gland morphogenesis |
| 105 | 6 | 6.35E-06 | male sex differentiation |
| 98 | 6 | 4.26E-06 | development of primary male sexual characteristics |
| 240 | 9 | 9.75E-07 | epithelial cell differentiation |
| 33 | 5 | 2.94E-07 | genitalia development |
| 21 | 4 | 1.86E-06 | male genitalia development |
| 290 | 9 | 4.61E-06 | regionalization |
| 190 | 9 | 1.36E-07 | anterior/posterior pattern formation |
| 333 | 13 | 1.90E-09 | skeletal system development |
| 94 | 6 | 3.34E-06 | embryonic skeletal system development |
| 133 | 11 | 1.28E-11 | appendage development |
| 127 | 11 | 7.71E-12 | appendage morphogenesis |
| 133 | 11 | 1.28E-11 | limb development |
| 127 | 11 | 7.71E-12 | limb morphogenesis |
| 30 | 5 | 1.78E-07 | hindlimb morphogenesis |
| 29 | 5 | 1.49E-07 | forelimb morphogenesis |
| 811 | 14 | 9.50E-06 | embryo development |
| 442 | 12 | 4.41E-07 | embryonic morphogenesis |
| 111 | 11 | 1.73E-12 | embryonic appendage morphogenesis |
| 111 | 11 | 1.73E-12 | embryonic limb morphogenesis |
| 24 | 4 | 3.28E-06 | embryonic forelimb morphogenesis |
| 751 | 14 | 3.95E-06 | sequence-specific DNA binding |
Enrichment was calculated using g:Profiler on the list of 93 human RefSeq protein IDs corresponding to amputation-specific genes selected by two-way ANOVA analysis. 85 IDs from the list of 93 were recognized as unambiguous and were used to calculate the enrichment. Columns represent: #Array: total number of genes present on the array, that is associated to functional term, #List: number of genes in the input list that are associated to functional term, P-value: enrichment P-value, GO term: term name. The vertical alignment of the term name depicts its depth in the GO term hierarchy.