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. 2013 May 1;8(5):e62422. doi: 10.1371/journal.pone.0062422

Table 2. Adjusted Hazard Ratios (HR) of Dementia Because of mTBI.

Variables Hazard ratio 95% confidence interval P-value
mTBI 3.26 2.69–3.94 <0.001
Male 0.65 0.57–0.73 <0.001
Patient age 1.12 1.11–1.12 <0.001
Charlson Comorbidity Index Score
0 1
1 1.29 1.06–1.56 0.01
≥2 1.47 1.21–1.79 <0.001
Diabetes 1.47 1.27–1.69 <0.001
Hypertension 1.06 0.92–1.22 0.445
Coronary artery disease 1.00 0.87–1.15 0.995
Hyperlipidemia 0.90 0.78–1.04 0.157
History of alcohol intoxication 1.12 0.53–2.36 0.766
Ischemic stroke 2.05 1.43–2.94 <0.001
Intracranial hemorrhage 1.43 1.24–1.66 <0.001
Socioeconomic status
Low 1
Moderate 0.73 0.62–0.84 <0.001
High 0.26 0.13–0.52 0.002
Urbanization level
Urban 1
Suburban 1.22 1.04–1.42 0.014
Rural 1.22 1.02–1.45 0.027