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. 2013 May 1;8(5):e62422. doi: 10.1371/journal.pone.0062422

Table 3. Adjusted Hazard Ratios (HR) of Dementia Because of mTBI in Patients Older than 65 Years.

Variables Hazard ratio 95% confidence interval P-value
mTBI 3.27 2.67–4.00 <0.001
Male 0.62 0.54–0.71 <0.001
Patient age 1.08 1.07–1.09 <0.001
Charlson Comorbidity Index Score
0 1
1 1.26 1.02–1.56 0.031
≥2 1.43 1.16–1.77 0.001
Diabetes 1.36 1.17–1.58 <0.001
Hypertension 0.99 0.85–1.14 0.839
Coronary artery disease 1.04 0.90–1.21 0.559
Hyperlipidemia 0.83 0.71–0.97 0.017
History of alcohol intoxication 1.48 0.70–3.12 0.303
Ischemic stroke 1.47 0.95–2.28 0.084
Intracranial hemorrhage 1.39 1.20–1.62 <0.001
Socioeconomic status
Low 1
Moderate 0.79 0.67–0.93 0.005
High 1.05 0.43–2.53 0.922
Urbanization level
Urban 1
Suburban 1.17 0.99–1.38 0.070
Rural 1.11 0.92–1.35 0.276