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. 2013 May 1;8(5):e58977. doi: 10.1371/journal.pone.0058977

Table 1. Top predictions for Catapult.

Leukemia Alzheimer disease Insulin resistance Prostate cancer
MIM:601626 MIM:104300 MIM:125853 MIM:176807
FGFR3 (2261) ACE2 (59272) INSR (3643) TP53 (7157)
FGFR2 (2263) COL1A1 (1277) INS (3630) RB1 (5925)
KRAS (3845) COL1A2 (1278) PTEN (5728) CTNNB1 (1499)
TP53 (7157) KRAS (3845) TP53 (7157) BRCA1 (672)
EGFR (1956) EGFR (1956) CTNNB1 (1499) KRAS (3845)
FGFR1 (2260) TP53 (7157) KRAS (3845) PIK3CA (5290)
PTPN11 (5781) AGT (183) AKT1 (207) AKT1 (207)
CTNNB1 (1499) PLAT (5327) CREBBP (1387) INSR (3643)
INSR (3643) APOE (348) EGFR (1956) NRAS (4893)
CREBBP (1387) PTGS2 (5743) PIK3CA (5290) RAD51 (5888)

Top 10 predictions not in the training set by Catapult for the eight OMIM phenotypes with the highest number of gene associations. Any gene which is among the top 10 candidates for more than one disease is marked in bold. Catapult does make a great number of very reasonable predictions as observed below. For example, it seems quite likely that both insulin receptor (INSR, 3643) and insulin (INS, 3630) should be associated with insulin resistance, and that many growth factor receptors have been associated with various cancers.