Table 1. Local maxima of regions with altered connectivity within the ECN and SMN.
RSN | Contrast | Region | Area | Side | X | Y | Z | p-value | Cluster size (voxels) |
Executive control network | Pt = 0> C | Superior medial gyrus | 8 | Left | 0 | 32 | 54 | 0.003 | 4353 |
Superior frontal gyrus | 6 | Right | 16 | 34 | 56 | 0.004 | |||
8/9 | 18 | 44 | 42 | 0.004 | |||||
6 | Left | −14 | 28 | 56 | 0.004 | ||||
9/10 | −20 | 60 | 6 | 0.006 | |||||
Middle frontal gyrus | 8/9 | Right | 36 | 36 | 36 | 0.004 | |||
Mid orbital gyrus | 11 | Right | 6 | 56 | −2 | 0.006 | |||
Anterior cingulate cortex | 25/32 | Right | 4 | 44 | 12 | 0.006 | |||
Left | −8 | 44 | 12 | 0.005 | |||||
Rectal gyrus | 11 | Left | −10 | 46 | −16 | 0.010 | |||
Paracentral lobule | 4/6 | Left | −6 | −32 | 62 | 0.005 | 450 | ||
Middle cingulate cortex | 6 | Left | 0 | −14 | 44 | 0.006 | |||
Postcentral gyrus | 2/3b | Left | −44 | −26 | 48 | 0.006 | 150 | ||
OP4 | −54 | −10 | 14 | 0.010 | 6 | ||||
Calcarine gyrus | V1 | Left | −6 | −84 | 6 | 0.010 | 53 | ||
Cuneus | V2 | Left | 4 | −84 | 20 | 0.010 | 26 | ||
Sensori-motor network | C >Pt = 0 | Superior frontal gyrus | 8/9 | Left | −2 | 46 | 36 | 0.005 | 761 |
8/9 | Right | 6 | 62 | 22 | 0.012 | ||||
Superior medial gyrus | 8/9 | Right | 14 | 44 | 38 | 0.008 | |||
Anterior cingulate cortex | 25/32 | Right | 6 | 46 | 28 | 0.012 | |||
SMA | 6 | Right | 4 | −24 | 54 | 0.008 | 100 | ||
Precuneus | 5 M | Left | −4 | −42 | 56 | 0.012 | 2 |
C = controls, OP = operculum, P = patients, RSN = resting state network, SMA = supplementary motor area. Between-group effects are corrected for family-wise errors (p≤0.013).