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. 2013 May 1;8(5):e63146. doi: 10.1371/journal.pone.0063146

Figure 2. VEGF overexpression increases the invasiveness of MCF-7 cells.

Figure 2

(a) Representative MR images of Matrigel® acquired from a MR compatible perfusion chamber over 48 h, which demonstrate significant Matrigel® degradation by MCF-7-VEGF (lower panel) cells in contrast to MCF-7 cells. (b) The time-dependent invasion indices showed a significant (*p = 0.024, p = 0.026 and p = 0.025, respectively with the two-tailed Aspin-Welch Unequal-Variance Test) increase in invasion by MCF-7-VEGF cells compared to MCF-7cells, at 1, 1.5 and 2 days.