Table 3. Summary of shifts (>32%) in the relative proportions of Firmicutes and Bacteroidetes for subjects with dissimilar samples, and all shifts observed for subjects who did not undergo colonoscopy.
Subject | Indication* | Dissimilar sample** | Sample comparisons*** | ||
−1m vs −1w | −1m vs LS | −1w vs LS | |||
3 | UC | 2 | 38 ↑ | 20 ↓ | 18 ↑ |
5 | UC | 5 | 22 ↓ | 77 ↑ | 55 ↑ |
7 | AP | 2 | 44 ↓ | 46 ↑ | 2 ↑ |
8 | AP | 2 | 24 ↓ | 9 ↓ | 33 ↓ |
9 | UC | 4 | 26 ↑ | 39 ↑ | 39 ↑ |
15 | FHCRC, PP | 2 | 32 ↓ | 44 ↑ | 12 ↑ |
A | N/A | – | 32 ↑ | – | – |
B | N/A | – | 7 ↓ | – | – |
C | N/A | – | 10 ↑ | – | – |
H | N/A | – | 4 ↑ | – | – |
W | N/A | – | 26 ↑ | – | – |
Abbreviations for indications for colonoscopy: UC, ulcerative colitis, AP, abdominal pain, FHCRC, family history of colorectal cancer, PP, previous polyps, N/A, did not undergo colonoscopy; indication not applicable.
Sample most dissimilar to other sample(s) from the same subject.
Values showing shifts (%) in Firmicutes and Bacteroidetes phyla for samples obtained from the same patient at different time points, ↑, increase in Firmicutes relative to the first sample, ↓, decrease in Firmicutes relative to the first sample for each comparison. For subjects who underwent colonoscopy: −1m, −1w, sample obtained one month, one week pre-colonoscopy, and LS refers to the last sample obtained post-colonoscopy (refer to Table 3), respectively. For subjects who did not undergo colonoscopy: +3m, sample obtained 3–6 months after the first sample.