Table 3. Summary of shifts (>32%) in the relative proportions of Firmicutes and Bacteroidetes for subjects with dissimilar samples, and all shifts observed for subjects who did not undergo colonoscopy.

Subject	Indication*	Dissimilar sample**	Sample comparisons***
			−1m vs −1w	−1m vs LS	−1w vs LS
3	UC	2	38 ↑	20 ↓	18 ↑
5	UC	5	22 ↓	77 ↑	55 ↑
7	AP	2	44 ↓	46 ↑	2 ↑
8	AP	2	24 ↓	9 ↓	33 ↓
9	UC	4	26 ↑	39 ↑	39 ↑
15	FHCRC, PP	2	32 ↓	44 ↑	12 ↑
A	N/A	–	32 ↑	–	–
B	N/A	–	7 ↓	–	–
C	N/A	–	10 ↑	–	–
H	N/A	–	4 ↑	–	–
W	N/A	–	26 ↑	–	–

^*Abbreviations for indications for colonoscopy: UC, ulcerative colitis, AP, abdominal pain, FHCRC, family history of colorectal cancer, PP, previous polyps, N/A, did not undergo colonoscopy; indication not applicable.

^**Sample most dissimilar to other sample(s) from the same subject.

^***Values showing shifts (%) in Firmicutes and Bacteroidetes phyla for samples obtained from the same patient at different time points, ↑, increase in Firmicutes relative to the first sample, ↓, decrease in Firmicutes relative to the first sample for each comparison. For subjects who underwent colonoscopy: −1m, −1w, sample obtained one month, one week pre-colonoscopy, and LS refers to the last sample obtained post-colonoscopy (refer to Table 3), respectively. For subjects who did not undergo colonoscopy: +3m, sample obtained 3–6 months after the first sample.