Table 1.
Vehicle (ICV) | sgp130 (100 ng) (ICV) | p-value | |||||
---|---|---|---|---|---|---|---|
| |||||||
Saline (i.p.) | LPS (10 μg) (i.p.) | Saline (i.p.) | LPS (10μg) (i.p.) | sgp130 | LPS | sgp130 × LPS | |
Adult | |||||||
Food intake (g/d) | 6.86± 0.62 | 4.18± 0.20 | 7.65± 0.36 | 3.88± 0.61 | 0.773 | <0.001* | 0.917 |
Δ Body wt. (g) | −0.33± 0.10 | −2.56± 0.19 | −0.26± 0.10 | −2.18± 0.25 | 0.632 | <0.001* | 0.861 |
| |||||||
Aged | |||||||
Food intake (g/d) | 6.89± 0.89 | 3.43± 0.145 | 7.14± 0.33 | 5.11± 0.47 | 0.868 | 0.002* | 0.039* |
Δ Body wt. (g) | −0.56± 0.13 | −3.40± 0.25 | −0.23± 0.33 | −2.79± 0.36 | 0.592 | <0.0001* | 0.041* |
a significant difference per treatment group