Skip to main content
. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Addict Biol. 2013 Jan 30;18(5):786–799. doi: 10.1111/adb.12038

Figure 6. Drug Substitution: 4-MMC in d-methamphetamine (MA)-trained rats.

Figure 6

Mean number of reward-lever responses and cumulative drug intakes (mg/kg) of 4-MMC for a group of Sprague-Dawley rats (N = 8) trained to self-administer MA (0.1 mg/kg/inf; FR2). Data for the MA training dose in the three days before the dose-substitution are included for comparison. Statistically reliable differences from all other 4-MMC conditions are indicated by the * symbol, from 0.05–0.5 by the # symbol and from 0.05–0.1 by the & symbol. Error bars represent ±SEM.