. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: Brain Behav Immun. 2013 Feb 4;30:125–132. doi: 10.1016/j.bbi.2013.01.081

Table 2.

Adjusted mean^* level of inflammatory markers, according to lifetime history of PTSD

Marker (units)	N	Age-Adjusted			Fully Adjusted^**			Fully Adjusted + Depression^***
Marker (units)	N	Mean, No PTSD (95% CI)	Mean, PTSD (95% CI)	P	Mean, No PTSD (95% CI)	Mean, PTSD (95% CI)	P	Mean, No PTSD (95% CI)	Mean, PTSD (95% CI)	P
hsCRP (mg/l)	471	1.30 (1.14–1.50)	1.97 (1.46–2.65)	0.008	1.31 (1.16–1.49)	1.77 (1.34–2.34)	0.041	1.31 (1.16–1.49)	1.75 (1.31–2.34)	0.060
IL-6 (pg/ml)	468	1.60 (1.47–1.74)	1.39 (1.12–1.71)	0.212	1.61 (1.48–1.74)	1.26 (1.01–1.56)	0.032	1.62 (1.49–1.75)	1.25 (1.00–1.56)	0.031
Fibrinogen (mg/dl)	445	340 (331–349)	345 (323–369)	0.993	340 (332–349)	339 (317–361)	0.564	341 (332–350)	333 (312–356)	0.346
WBC (10³/μ1)	446	6.19 (6.01–6.38)	6.26 (5.83–6.71)	0.790	6.21 (6.04–6.38)	6.14 (5.74–6.56)	0.754	6.22 (6.05–6.39)	6.03 (5.62–6.46)	0.398
VCAM-1 (ng/ml)	470	589 (567–611)	598 (546–654)	0.898	586 (567–606)	609 (557–667)	0.795	589 (567–612)	602 (549–660)	0.596
ICAM-1 (ng/ml)	470	292 (284–303)	324 (300–349)	0.004	294 (285–303)	314 (292–337)	0.040	294 (285–303)	315 (292–340)	0.024

hsCRP, high-sensitivity C-reactive protein; IL-6, interleukin 6; WBC, white blood cell; ICAM-1, intercellular adhesion molecule 1; VCAM-1, vascular cell adhesion molecule 1.

Geometric means.

^**

Adjusted for age, physical activity, current smoking, alcohol intake, aspirin use, statin use, diabetes, hypertension, and body mass index.

^***

Adjusted for age, physical activity, current smoking, alcohol intake, aspirin use, statin use, diabetes, hypertension, body mass index, and lifetime history of depression.