Table 3.
Adjusted mean level of inflammatory markers, according to PTSD status (no PTSD, past PTSD, and current PTSD).
| Marker | N | Mean (95% CI) | ||
|---|---|---|---|---|
| Age-Adjusted | Fully Adjusted** | Fully Adjusted*** | ||
| hsCRP (mg/l) | 471 | |||
| No PTSD | 1.30 (1.14, 1.49) | 1.31 (1.16, 1.48) | 1.31 (1.16, 1.49) | |
| Past PTSD | 1.53 (1.07, 2.19) | 1.42 (1.01, 1.99) | 1.40 (1.00, 1.98) | |
| Current PTSD | 2.87 (1.86, 4.41) | 2.47 (1.64, 3.71) | 2.45 (1.61, 3.71) | |
| Ptrend | <0.001 | 0.007 | 0.010 | |
| IL-6 (pg/ml) | 468 | |||
| No PTSD | 1.59 (1.47, 1.73) | 1.61 (1.48, 1.74) | 1.61 (1.49, 1.75) | |
| Past PTSD | 1.24 (0.95, 1.63) | 1.12 (0.85, 1.47) | 1.11 (0.85, 1.47) | |
| Current PTSD | 1.61 (1.17, 2.21) | 1.48 (1.07, 2.03) | 1.47 (1.06, 2.04) | |
| Ptrend | 0.470 | 0.131 | 0.136 | |
| Fibrinogen (mg/dl) | 445 | |||
| No PTSD | 340 (331, 350) | 341 (333, 350) | 341 (333, 350) | |
| Past PTSD | 331 (306, 358) | 326 (302, 352) | 323 (299, 349) | |
| Current PTSD | 355 (324, 388) | 348 (318, 380) | 343 (313, 375) | |
| Ptrend | 0.647 | 0.921 | 0.651 | |
| WBC (103/μ1) | 446 | |||
| No PTSD | 6.19 (6.01, 6.38) | 6.21 (6.04, 6.38) | 6.22 (6.05, 6.39) | |
| Past PTSD | 6.21 (5.68, 6.8) | 6.08 (5.59, 6.62) | 6 (5.51, 6.53) | |
| Current PTSD | 6.31 (5.71, 6.97) | 6.21 (5.65, 6.84) | 6.07 (5.51, 6.69) | |
| Ptrend | 0.735 | 0.880 | 0.488 | |
| VCAM-1 (ng/ml) | 470 | |||
| No PTSD | 589 (567, 612) | 588 (566, 611) | 588 (566, 611) | |
| Past PTSD | 601 (541, 669) | 595 (537, 659) | 601 (541, 667) | |
| Current PTSD | 578 (509, 658) | 595 (525, 675) | 605 (533, 688) | |
| Ptrend | 0.952 | 0.806 | 0.599 | |
| ICAM-1 (ng/ml) | 470 | |||
| No PTSD | 292 (283, 302) | 293 (284, 302) | 293 (284, 302) | |
| Past PTSD | 325 (298, 354) | 314 (288, 342) | 317 (290, 345) | |
| Current PTSD | 327 (294, 364) | 320 (288, 355) | 324 (292, 360) | |
| Ptrend | 0.007 | 0.045 | 0.027 | |
hsCRP, high-sensitivity C-reactive protein; IL-6, interleukin 6; WBC, white blood cell; ICAM-1, intercellular adhesion molecule 1; VCAM-1, vascular cell adhesion molecule 1.
*
Geometric means.
**
Adjusted for age, physical activity, current smoking, alcohol intake, aspirin use, statin use, diabetes, hypertension, and body mass index.
***
Adjusted for age, physical activity, current smoking, alcohol intake, aspirin use, statin use, diabetes, hypertension, body mass index, and lifetime history of depression.