Table 3.
Outcome variable | mean (standard error)4 | PGroup effect | Estimated effect size (95% CI)5 | |
---|---|---|---|---|
Sham N=21 | Active N=48 | |||
HCS2 (primary) | 8.37 (0.76) | 6.55 (0.48) | 0.044 | 0.54 (0.02 – 1.06) |
Hallucination frequency difference3 | −0.06 (0.37) | −1.31 (0.24) | 0.005 | 0.74 (0.23 – 1.26) |
Total AHRS Difference3 | −1.90 (1.16) | −4.11 (0.76) | 0.11 | 0.42 |
CGI2 | 3.58 (0.29) | 2.73 (0.18) | 0.013 | 0.67 (0.14 – 1.18) |
Model includes group and site (W versus rW, corresponding to optimal response); based on data collected after the third 5-session block, with multiple imputations used for missing data
Lower scores correspond to greater improvement; all HCS were 10 at baseline; no baseline for CGI, scores range from 1 to 7, with 4 = no change.
Difference = baseline − endpoint; lower scores correspond to greater improvement
Model-based least-square means and standard errors
95% confidence intervals provided for comparisons with p <0.05