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. Author manuscript; available in PMC: 2014 Jan 29.
Published in final edited form as: Biochemistry. 2013 Jan 15;52(4):752–764. doi: 10.1021/bi300723f

Table 1.

Novel designed cyclic γ-MSH analogues

LIGAND SEQUENCE RING SIZE
Peptide 1 c(CH2-CO-Gly-His-D-Phe-Arg-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 21
Peptide 2 c(CH2-CO-Gly-His-D-Phe-Arg-D-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 21
Peptide 3 c(C2H4-CO-Gly-His-D-Phe-Arg-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 22
Peptide 4 c(C2H4-CO-Gly-His-D-Phe-Arg-D-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 22
Peptide 5 c(C3H6-CO-Gly-His-D-Phe-Arg-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 23
Peptide 6 c(C3H6-CO-Gly-His-D-Phe-Arg-D-Trp-Cys)-Asp-Arg-Phe-Gly-NH2 23