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Immunohistochemical examination of tumor tissues derived from control and NVP-LDE-225-treated NOD/SCID IL2Rγ null mice. Tumor samples derived from control and treated mice (as described in Materials and methods) were subjected to immunohistochemistry with anti-Gli1, anti-Gli2, anti-Patched-1, anti-Patched-2, anti-PCNA, anti-Bmi-1, anti-cMyc, anti-Cyclin D1, anti-Snail or anti-Bcl-2 antibody.
