Figure 8.

Kaplan–Meier survival analyses reveal the clinical relevance of IF1. (a) Protein samples from breast tumor biopsies were analyzed by western blot for the expression level of IF1. Kaplan–Meier disease-free survival analysis for 93 breast cancer patients stratified by the tumor expression level of IF1. The plot shows a significant association of low IF1 expression with a poor outcome for the patients. The log-rank test P-value is shown. (b) Protein samples from normal and tumor biopsies from a cohort of patients with colorectal cancer were analyzed by reverse phase protein microarrays to quantify IF1 (see Supplementary Figure S4). Kaplan–Meier overall survival analysis for 38 colon cancer patients stratified by the tumor quantity of IF1. The plot shows a significant association of low IF1 expression with a poor outcome for the patients. The log-rank test P-value is shown.