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PLS-DA models for separation between AD, MCI and CN. (a) Separation between AD and CN; (b) separation between MCI and CN. Examples of PLS-DA models cross-validation: (c) AD versus CN and (d) MCI versus CN. A, Alzheimer's disease; AD, Alzheimer's disease; C, normal cognition; CN, normal cognition; M, mild cognitive impairment; MCI, mild cognitive impairment; PLS-DA, partial least square-discriminant analysis.
