Skip to main content
. 2013 May 2;4:70. doi: 10.3389/fgene.2013.00070

Table 7.

Association between genetic polymorphism and development of cervical cancer.

Type of polymorphism Genotype Cervical cancer, persons (%) Control, persons (%) Odds ratio (OR) Confidence interval (CI), (95%) χ2 p
GSTT1 +/+ 12 (5.53) 57 (35.62) 0.11 0.05–0.21 67.15 0.00
± 76 (35.02) 60 (37.50) 0.90 0.59–1.37
−/− 129 (59.45) 43 (26.88) 3.99 2.56–6.21
GSTM1 +/+ 108 (49.77) 116 (72.50) 0.38 0.24–0.58 25.31 <0.0001
± 78 (35.94) 40 (25.00) 1.68 1.07–2.65
−/− 31 (14.29) 4 (2.5) 6.5 2.25–18.81
XRCC1 Arg194Trp Arg/Arg 163 (75.12) 105 (65.63) 1.58 1.01–2.48 8.72 0.01
Arg/Trp 48 (22.12) 40 (25.00) 0.85 0.53–1.38
Trp/Trp 6 (2.76) 15 (9.37) 0.27 0.10–0.73
XRCC1 Arg399Gln Arg/Arg 78 (35.94) 66 (41.25) 0.80 0.53–1.22 7.24 0.03
Arg/Gln 119 (54.84) 90 (56.25) 0.94 0.63–1.42
Gln/Gln 20 (9.22) 4 (2.50) 3.96 1.33–11.82
XRCC3 Trp241Met Trp/Trp 140 (64.51) 124 (77.50) 0.53 0.33–0.84 10.28 0.006
Trp/Met 57 (26.27) 32 (20.00) 1.43 0.87–2.33
Met/Met 20 (9.22) 4 (2.50) 3.96 1.33–11.82
TP53 Arg72Pro Arg/Arg 85 (39.17) 49 (30.63) 1.46 0.95–2.25 5.15 0.08
Arg/Pro 111 (51.15) 85 (53.12) 0.92 0.61–1.39
Pro/Pro 21 (9.68) 26 (16.25) 0.55 0.30–1.02
CCND1 A870G G/G 54 (25.12) 41 (25.62) 0.97 0.61–1.56 0.09 0.96
G/A 103 (47.91) 78 (48.75) 0.97 0.64–1.46
A/A 58 (26.97) 41 (25.63) 1.07 0.67–1.71