Table 7.
Type of polymorphism | Genotype | Cervical cancer, persons (%) | Control, persons (%) | Odds ratio (OR) | Confidence interval (CI), (95%) | χ2 | p |
---|---|---|---|---|---|---|---|
GSTT1 | +/+ | 12 (5.53) | 57 (35.62) | 0.11 | 0.05–0.21 | 67.15 | 0.00 |
± | 76 (35.02) | 60 (37.50) | 0.90 | 0.59–1.37 | |||
−/− | 129 (59.45) | 43 (26.88) | 3.99 | 2.56–6.21 | |||
GSTM1 | +/+ | 108 (49.77) | 116 (72.50) | 0.38 | 0.24–0.58 | 25.31 | <0.0001 |
± | 78 (35.94) | 40 (25.00) | 1.68 | 1.07–2.65 | |||
−/− | 31 (14.29) | 4 (2.5) | 6.5 | 2.25–18.81 | |||
XRCC1 Arg194Trp | Arg/Arg | 163 (75.12) | 105 (65.63) | 1.58 | 1.01–2.48 | 8.72 | 0.01 |
Arg/Trp | 48 (22.12) | 40 (25.00) | 0.85 | 0.53–1.38 | |||
Trp/Trp | 6 (2.76) | 15 (9.37) | 0.27 | 0.10–0.73 | |||
XRCC1 Arg399Gln | Arg/Arg | 78 (35.94) | 66 (41.25) | 0.80 | 0.53–1.22 | 7.24 | 0.03 |
Arg/Gln | 119 (54.84) | 90 (56.25) | 0.94 | 0.63–1.42 | |||
Gln/Gln | 20 (9.22) | 4 (2.50) | 3.96 | 1.33–11.82 | |||
XRCC3 Trp241Met | Trp/Trp | 140 (64.51) | 124 (77.50) | 0.53 | 0.33–0.84 | 10.28 | 0.006 |
Trp/Met | 57 (26.27) | 32 (20.00) | 1.43 | 0.87–2.33 | |||
Met/Met | 20 (9.22) | 4 (2.50) | 3.96 | 1.33–11.82 | |||
TP53 Arg72Pro | Arg/Arg | 85 (39.17) | 49 (30.63) | 1.46 | 0.95–2.25 | 5.15 | 0.08 |
Arg/Pro | 111 (51.15) | 85 (53.12) | 0.92 | 0.61–1.39 | |||
Pro/Pro | 21 (9.68) | 26 (16.25) | 0.55 | 0.30–1.02 | |||
CCND1 A870G | G/G | 54 (25.12) | 41 (25.62) | 0.97 | 0.61–1.56 | 0.09 | 0.96 |
G/A | 103 (47.91) | 78 (48.75) | 0.97 | 0.64–1.46 | |||
A/A | 58 (26.97) | 41 (25.63) | 1.07 | 0.67–1.71 |