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. 2013 Jan 31;8(5):739–748. doi: 10.2215/CJN.02410312

Table 4.

Interaction of practitioner characteristics and report format with undocumented CKD

Variable OR for Undocumented CKD (95% CI): Adjusted OR from Models Stratified by Report Formata OR for Undocumented CKD (95% CI): Adjusted OR from Model with Interaction Termsb Pb
SCr Only eGFR SCr Only eGFR
Sex Sex × format 0.09
 Female (REF: male) 3.79 (2.28, 6.29) 2.15 (1.29, 3.56)  Female (REF: male) 3.74 (2.37, 5.92) 2.27 (1.45, 3.56)
Experience (yr) Experience × format 1.10 (0.60, 2.03) 0.39 (0.19, 0.78)c 0.03
 <20 (REF: 20+) 0.94 (0.49, 1.80) 0.34 (0.22, 0.54)  <20 (REF: 20+)
Clinician training Training × format 0.03
 NP/PA (REF: MD/DO) 2.16 (0.96, 4.87) 0.80 (0.42, 1.54)  NP/PA (REF: MD/DO) 2.40 (1.08, 7.94) 0.59 (0.30, 1.20)d
eGFR at inclusion (ml/min per 1.73 m2) eGFR at inclusion (ml/min per 1.73 m2) <0.01
 40–59 (REF: <30) 10.58 (3.85, 29.04) 9.26 (3.96, 21.64)  40–59 (REF: <30) 9.77 (4.77, 20.0)
 30–44 (REF: <30) 5.59 (2.63, 11.92) 3.50 (1.93, 6.36)  30–44 (REF: <30) 4.47 (2.61, 7.67)
Comorbidity Comorbidity
 No DM (REF: DM) 1.38 (0.94, 2.01) 1.03 (0.68, 1.57)  No DM (REF: DM) 1.29 (1.01, 1.66) 0.05
 No HTN (REF: HTN) 2.45 (1.33, 4.53) 1.29 (0.75, 2.22)  No HTN (REF: HTN) 1.52 (1.03, 2.25) 0.04
Age (yr) Age (yr) 0.02
 <60 (REF: 85+) 0.68 (0.29, 1.59) 0.80 (0.36, 1.78)  <60 (REF: 85+) 0.75 (0.40, 1.38)
 60–74 (REF: 85+) 0.56 (0.30, 1.02) 0.53 (0.30, 0.95)  60–74 (REF: 85+) 0.55 (0.36, 0.84)
 75–84 (REF: 85+) 0.86 (0.56, 1.32) 1.26 (0.73, 2.17)  75–84 (REF: 85+) 0.99 (0.72, 1.36)

OR, odds ratio; CI, confidence interval; SCr, serum creatinine; eGFR, estimated GFR; REF, reference category for OR; NP, nurse practitioner; PA, physician assistant; MD, doctor of medicine; DO, doctor of osteopathic medicine; DM, diabetes mellitus; HTN, hypertension.

a

Variables included in the model: sex, eGFR at inclusion, age, laboratory report format, presence of DM, presence of HTN, and practitioner degree.

b

Variables included in the model: sex, eGFR at inclusion, age, laboratory report format, presence of DM, presence of HTN, and practitioner degree. Interactions included in the model: laboratory report format × sex, laboratory report format × practitioner degree, and laboratory report format × clinician experience; P values are the significance levels for the factors and interaction terms.

c

Differences between OR in SCr only and eGFR (P=0.03).

d

Differences between OR in SCr only and eGFR (P=0.01).