Table 2.
Characteristics of all renal transplant patients with ESRD secondary to ANCA-associated vasculitis or other causes in Australia and New Zealand during the period 1996–2010
| Characteristic | Granulomatosis with Polyangiitis (n=47) | Microscopic Polyangiitis (n=46) | Other ESRD (n=8193) | P Value |
|---|---|---|---|---|
| Age (yr) | 46.5±14.5 | 52.8±15.8 | 44.1±15.4 | <0.001 |
| Male | 33 (70) | 28 (61) | 5076 (62) | 0.50 |
| Racial origin | 0.08 | |||
| European | 45 (96) | 44 (96) | 6722 (82) | |
| ATSI | 0 (0) | 0 (0) | 241 (3) | |
| MPI | 0 (0) | 0 (0) | 341 (4) | |
| Asian | 2 (4) | 0 (0) | 524 (6) | |
| Other | 0 (0) | 2 (4) | 365 (5) | |
| Transplant era | 0.41 | |||
| 1996–2000 | 15 (32) | 17 (37) | 1543 (19) | |
| 2001–2005 | 24 (51) | 18 (39) | 2937 (36) | |
| 2006–2010 | 8 (17) | 11 (24) | 3713 (45) | |
| Ever smoked | 0.56 | |||
| Current | 3 (6) | 7 (15) | 873 (11) | |
| Former | 14 (30) | 18 (39) | 2423 (30) | |
| Never | 30 (64) | 21 (46) | 4890 (60) | |
| Missing | 0 (0) | 0 (0) | 7 (0) | |
| Hypertension | 0.64 | |||
| Yes | 27 (57) | 29 (63) | 4879 (60) | |
| No | 8 (17) | 4 (9) | 859 (10) | |
| Missing | 12 (26) | 13 (28) | 2455 (30) | |
| Diabetes mellitus | 0.04 | |||
| Yes | 3 (6) | 3 (7) | 1323 (16) | |
| No | 44 (94) | 43 (94) | 6870 (84) | |
| Chronic lung disease | <0.001 | |||
| Yes | 6 (13) | 9 (20) | 352 (4) | |
| No | 41 (87) | 37 (80) | 7841 (96) | |
| Coronary artery disease | 0.57 | |||
| Yes | 6 (13) | 3 (7) | 749 (9) | |
| No | 41 (87) | 43 (94) | 7444 (91) | |
| Peripheral vascular disease | 0.19 | |||
| Yes | 5 (11) | 1 (2) | 458 (6) | |
| No | 42 (89) | 45 (98) | 7735 (94) | |
| Cerebrovascular disease | 0.40 | |||
| Yes | 3 (6) | 2 (4) | 256 (3) | |
| No | 44 (94) | 44 (96) | 7937 (97) | |
| BMI (kg/m2) | 24.9±4.0 | 26.1±4.6 | 25.3±5.2 | 0.68 |
| Late referral | <0.001 | |||
| Yes | 13 (28) | 18 (39) | 1338 (16) | |
| No | 34 (72) | 28 (61) | 6808 (83) | |
| Missing | 0 (0) | 0 (0) | 47 (1) | |
| Donor type | 0.76 | |||
| Deceased | 28 (57) | 25 (51) | 4748 (56) | |
| Living | 2 (43) | 24 (49) | 3694 (44) | |
| Subsequent grafts | 0.76 | |||
| Second | 2 (1) | 3 (1) | 254 (3) | |
| Third | 0 (0) | 0 (0) | 6 (0) |
Data are presented as mean ± SD, n (%), or median (range). ATSI, Aboriginal and Torres Strait Islander; MPI, Maori and Pacific Islander; BMI, body mass index; RRT, renal replacement therapy.