Table 4.
Cox regression model of factors associated with frequently relapsing nephrotic syndrome at 2 years after initial therapy (n=138)
Factor | Unadjusted | Adjusted | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Male (versus female) | 1.32 | 0.63–3.02 | 0.47 | 1.41 | 0.64–3.34 | 0.40 |
Onset age (<5 to ≥5 yr) | 2.69 | 1.31–5.94 | 0.007 | 1.50 | 0.71–3.39 | 0.29 |
Serum sodium (<135 to ≥135 mEq/L) | 2.54 | 1.15–5.22 | 0.02 | 1.34 | 0.59–2.83 | 0.47 |
Time from start of initial treatment to disappearance of proteinuria (≥9 to <9 d) | 6.65 | 3.17–15.19 | <0.001 | 3.09 | 1.42–7.27 | 0.004 |
Time from start of initial treatment to first relapse (<6 to ≥6 mo) | 8.66×106 | 29.46–N/A | <0.001 | 5.09×106 | 16.56–2.06×10184 | <0.001 |
HR, hazard ratio; CI, confidence interval; N/A, not available.